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4.4 Future directions Future research studies should prioritize longitudinal cohort designs to examine the directionality of associations between UPF consumption and mental health outcomes

Meanwhile, autophagy could be activated by rapamycin via PI3K/mTOR signaling pathway, and thus, protects hippocampal neurons from degeneration by decreasing the levels of prooxidants (Kotagale et al., 2020)

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While GLP-1(7-36)amide and GLP-1(7-37) are equally effective in stimulating insulin and C-peptide secretion, GLP-1(1-37) is much lower insulinotropic efficacy (88, 90, 94)